With over four years' experience in HbA1c testing by capillary electrophoresis separation, Sebia offers high-resolution testing on Capillarys 3 Tera, Capillarys 2 Flex Piercing, and Minicap Flex Piercing instruments for an accurate HbA1c measurement at very high speed.
From whole blood sampling in primary capped tubes to the final result, the instruments perform all sequences automatically. The clear-cut and precise separation of the different hemoglobin fractions allows accurate HbA1c measurement with no altered results in the presence of frequent interferences (labile A1c, carbamylated Hb, Hb F, Hb S, Hb C, Hb D and Hb E) as well as the incidental detection of the common haemoglobin disorders (sickle cell, beta-thalassemia, and more). Using the IFCC reference method calculation formula HbA1c/(HbA1c+HbA0), developed for the worldwide assay standardisation, the Sebia methodology ensures accurate and reliable results.
The HbA1c assay is based on the principle of capillary electrophoresis in free solution. Hemoglobin fractions are separated in silica capillaries, by their electrophoretic mobility and electroosmotic flow at a high voltage in an alkaline buffer. Hemoglobin fractions are directly detected at an absorbance of 415 nm.
Performance:
From whole blood sampling in primary capped tubes to the final result, the instruments perform all sequences automatically. The clear-cut and precise separation of the different hemoglobin fractions allows accurate HbA1c measurement with no altered results in the presence of frequent interferences (labile A1c, carbamylated Hb, Hb F, Hb S, Hb C, Hb D and Hb E) as well as the incidental detection of the common haemoglobin disorders (sickle cell, beta-thalassemia, and more). Using the IFCC reference method calculation formula HbA1c/(HbA1c+HbA0), developed for the worldwide assay standardisation, the Sebia methodology ensures accurate and reliable results.
The HbA1c assay is based on the principle of capillary electrophoresis in free solution. Hemoglobin fractions are separated in silica capillaries, by their electrophoretic mobility and electroosmotic flow at a high voltage in an alkaline buffer. Hemoglobin fractions are directly detected at an absorbance of 415 nm.
Performance:
- Capillarys 3 Tera: 70 tests per hour
- Capillarys 2 Flex Piercing: 38 tests per hour
- Minicap Flex Piercing: 8 tests per hour
- Between-run CVs: <2%
- Full traceability and positive ID for blood samples and reagents
- Cap piercing and tube mixing from primary tubes
- Rapid validation through colour coded profiles using the Phoresis mosaic screen.
Take a look at the Sebia range
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